THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
ARIIZUMI, Kiyoshi,CRUZ, Ponciano
申请号:
USUS2016/021472
公开号:
WO2016/145022A1
申请日:
2016.03.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell suppressor function of these cells, as well as their use in diagnosing and treating cancers such as melanoma.La présente invention concerne des anticorps qui se lient à DC-HIL sur la surface de cellules suppressives issues de myéloïde, et ainsi antagonisent la fonction de suppression des lymphocytes T de ces cellules, ainsi que leur utilisation dans le diagnostic et le traitement de cancers tels que le mélanome.