Flieg, Ralf,Knoer, Torsten,Freudemann, Wolfgang,Yildirim, Mehmet,Rempfer, Martin,Wagner, Steffen,Storr, Markus
申请号：
ES12194168
公开号：
ES2626754T3
申请日:
2012.11.26
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A module (1) of hollow fiber membrane to recover or remove therapeutically blood components of blood or blood products, comprising (a) a housing (2) of cylindrical filter (B) a bundle of membranes (3) of substantially parallel hollow fiber distributed longitudinally within the housing (2), wherein the open ends are in fluid communication with a distribution space (6a) and a collection space (6b ), and wherein the ends are encapsulated in a sealing compound (5) such that the open ends of the hollow fibers (3) extend through the sealing compound (5), and wherein the allocation fiber in the housing (2) cylindrical filter is between 15% and 70%, wherein the allocation of fiber is calculated from the percentage of the cross sectional area assigned by the fiber by the cross-sectional area usable in the filter housing (C) a filtering space (4) which it is closed distribution space (6a) and the collecting space (6b) and light space or opening of the membranes (3) hollow fiber having space filter means inlet and outlet (7a, 9) are closed (D) an inlet means (7b) for feeding the fluid to distribution space (6a) which is in fluid communication with the light side of the membranes (3) hollow fiber (E) a first output means (8) for removing treated the housing (2) fluid, first outlet means being in fluid communication with said collecting space (6b) characterized in that the filtrate space is populated homogeneously with a particulate material having an average diameter of from 10 .mu.m to 500 .mu.m and which is capable of interacting with at least one component of the fluid with a fill ratio of between 0, 6 and 1.0, wherein the filling ratio is the volume in ml of the maximum amount of particulate material is charged in the space filtering module (VPM) of hollow fiber membrane and the volume given ml usable space filtering said module (VFS): ** ** Formula wherein VPM represents the volume of particulate material stays in the filtering space module, and VFS represents the usable s
