ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES

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专利权人:

Samuel Hou;Darko Skegro;Stanislas Blein

发明人:

Stanislas Blein,Samuel Hou,Darko Skegro

申请号：

US13578921

公开号：

US20130052191A1

申请日:

2011.02.22

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to antibodies directed to α2β1 integrin and their uses, including humanized anti-alpha 2 (α2) integrin antibodies and methods of treatment with anti-α2integrin antibodies. More specifically the present invention relates to humanized anti-α2 integrin antibodies comprising a heavy chain variable region, a light chain variable region, a human light chain constant region and a variant human IgG1 heavy chain constant region which exhibit altered effector function.

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中国工程科技知识中心

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