医薬組成物
- 专利权人:
- 田辺三菱製薬株式会社
- 发明人:
- 原田 直之,彦田 匡毅
- 申请号：
- JP2007187893
- 公开号：
- JP5165950B2
- 申请日:
- 2007.07.19
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a pharmacological composition containing a compound having excellent GlyT2 inhibiting action as an active component.
SOLUTION: The pharmacological composition contains a norvaline derivative expressed by formula (I) or its pharmacologically allowable salt as an active component. In the formula, X is -CH
2 -, -O-, -S- or a single bond Ar is a (substituted)aryl or a (substituted)lower cycloalkyl n is an integer of 0-2 R1 , R2 , R3 and R4 are (i) each independently hydrogen atom or lower alkyl, (ii) R1 and R2 together form lower alkylene or (iii) R is -N(R5 )(R6 ) or -OR7 , R5 or R6 R5 and R6 are (i) each independently a lower alkyl which may be substituted with hydroxyl group, or hydrogen atom (ii) R5 and R6 together with adjacent nitrogen atom form a nitrogen-containing aliphatic 5 to 6-membered heterocyclic group which may have substituents and R7 is a lower alkyl group.COPYRIGHT: (C)2008,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
