A method and an ultrasound system are provided for generating transmission signals of an ultrasound probe used in a contrast-enhanced ultrasound image mode. The ultrasound system generates a pair of pulse control signals n and n+1 and a damping compensation pulse control signal, generates a pair of pulses n and n+1 having polarities opposite to each other and a damping compensation pulse having a polarity opposite to that of the n+1-th pulse based on the pair of pulse control signals and the damping compensation pulse control signal, transmits transmission signals including the pair of pulses and the damping compensation pulse, generates an ultrasound signal based on the transmission signals, transmits the ultrasound signal to a target object, and acquires echo signals for forming a contrast-enhanced ultrasound image of the target object. The damping compensation pulse is successively generated after generating the pair of pulses.
