A system for modeling electrical activity of an anatomical structure. The system includes a database that is configured to store cell set data corresponding to a group of cells of the anatomical structure. The cell set data includes a cell model that represents electrical activity of the group of cells. The cell model has a model parameter that relates to ion channels in the cells. The electrical activity represented by the cell model is at least partially based upon the model parameter. The system also includes a user interface that is configured to accept user inputs to change the model parameter and thereby change the electrical activity represented by the cell model to form a reconfigured cell model. The system also includes a display that is configured to display the user inputs and a processor that is configured to determine the electrical activity of the anatomical structure using the reconfigured cell model.