The invention relates to novel organic compounds of formula (I)and their use in the treatment of the animal or human body, to pharmaceutical compositions comprising a compound of formula I and to the use of a compound of formula I for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as in the treatment of tumour diseases and ocular neovascular diseases.本發明係關於一種新穎式(I)有機化合物,及其用於治療動物體或人體之用途,包含式I化合物之醫藥組合物,及式I化合物用於製備醫藥組合物之用途,該等醫藥組合物用於治療蛋白激酶依賴性疾病,尤其治療增生性疾病,諸如治療腫瘤疾病及眼部新生血管性疾病。