The present invention provides a novel compound or pharmaceutically acceptable salts thereof which has ability of inhibition of SIP lyase and induce the decrease of number of lymphocytes; and a pharmaceutical composition comprising the same. The compound is represented by following general formula (I), or the pharmaceutically acceptable salts thereof.本發明提供一種新穎化合物或其藥學上可容許之鹽,其具有S1P裂解酶抑制能力,且誘導淋巴球數之減少;及提供含有該等作為有效成分之醫藥組成物。其係通式(I)所示之化合物或其藥學上可容許之鹽: