LEE, SEULKI,POMPER, MARTIN G.,PARK, OGYI,SWIERCZEWSKA, MAGDALENA,PASRICHA, PANKAJ J.
申请号:
CA3020339
公开号:
CA3020339A1
申请日:
2017.04.07
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Death receptor 5 (DR5) agonist compositions and methods for treating pancreatitis have been developed. The compositions include Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL), its analogues, and anti-DR5 agonistic antibodies. In certain embodiments, TRAIL analogs and anti-death receptor 5 agonistic antibodies have analgesic and disease modifying effects on the pancreas.