THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODY CORPORATE
发明人:
HELMKE, STEVE MARK,EVERSON, GREGORY THOMAS
申请号:
CA2891281
公开号:
CA2891281A1
申请日:
2013.11.12
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.