Dindo Mijares;Deepak Saxena;Sudharani Bodepudi;Racquel Z. LeGeros;Haijing Gu
发明人:
Racquel Z. LeGeros,Haijing Gu,Dindo Mijares,Deepak Saxena,Sudharani Bodepudi
申请号：
US13433794
公开号：
US09005587B2
申请日:
2012.03.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides compositions including saturated calcium phosphate (sCaP) solutions, that may be prepared from mixtures of calcium deficient apatite and one or more of sodium fluoride and zinc chloride, or F or Zn ions. The solutions may be prepared from mixtures of calcium compounds and one or more of sodium or potassium phosphates, sodium or potassium fluoride and zinc salts with, for instance, either phosphoric or hydrochloric acids. Such compositions may be useful for increasing occlusion of dentin tubules, decreasing bacterial attachment to dentin tubules, decreasing bacterial growth or colonization on tooth surfaces such as enamel and dentin surfaces including on dentin tubules, increasing resistance to acid dissolution, inhibiting dental caries formation and progression and tooth decay and inhibiting development of tooth hypersensitivity.
