The University of Sydney;Sydney West Area Health Services (SWAHS)
发明人:
Collyer, Charles,Hunter, Neil
申请号：
AU2011214908
公开号：
AU2011214908A1
申请日:
2011.02.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present disclosure relates generally to a structure-modeling approach to identify therapeutic and diagnostic targets on proteins. Means are provided to generate agents which bind and optionally antagonize a particular domain within a protein referred to as a Family Domain. In an embodiment, the disclosure is directed to the control of infection or infection by related microorganisms by targeting selected domains on protease-like molecules having a hemagglutinin region. In another embodiment, the present invention enables the modulation or detection of a protein having a domain homologous to those in the protease-like molecules.
