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NOVEL POLYMORPHIC CRYSTAL FORMS OF 5-(2-{[6-(2,2-DIFLUORO-2-PHENYLETHOXY)HEXYL]AMINO}-1-(R)-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE, HEMINAPADISYLATE AS AGONIST OF THE �2 ADRENERGIC RECEPTOR.
专利权人:
ALMIRALL; S.A.
发明人:
AMAT MESTRES, GEMMA,BALAGUER ARDANUY, ELVIRA,CARRERA CARRERA, FRANCESC,MARCHUETA HEREU, IOLANDA,MOYES VALLS, ENRIQUE
申请号:
PH12014502097
公开号:
PH12014502097A1
申请日:
2014.09.22
申请国别(地区):
PH
年份:
2014
代理人:
摘要:
The present invention is directed to novel polymorphic crystal forms of a 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, heminapadisylate. The invention is also directed to pharmaceutical compositions comprising said polymorphic crystal forms, methods of using them to treat respiratory diseases associated with �2 adrenergic receptor activity and a process for preparing such polymophic crystal forms.
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