Federalnoe gosudarstvennoe byudzhetnoe uchrezhdenie "Natsionalnyj meditsinskij issledovatelskij tsentr travmatologii i ortopedii imeni N.N. Priorova" Ministerstva zdravookhraneniya Rossijskoj Federats
发明人:
Ochkurenko Aleksandr Alekseevich (RU),Очкуренко Александр Алексеевич (RU),Snetkov Andrej Igorevich (RU),Снетков Андрей Игоревич (RU),Akinshina Aleksandra Dmitrievna (RU),Акиньшина Александра Дмитриевн
申请号：
RU2018118606
公开号：
RU0002699742C1
申请日:
2018.05.21
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to traumatology and orthopedics, and can be used for complex treatment of primary chronic recurrent osteomyelitis in children on a background of somatic status. In preoperative period before radical removal of inflammatory focus is determined by multilayer spiral computed tomography spatial visualization of chronic osteomyelitis affected patient's bone structures. Magnetic resonance tomography is used to assess the extent of their damage, as well as the state of surrounding soft tissues, including the state of their vascular network, which are not visualized when performing multilayer spiral computed tomography. Then, in any sequence, presence or absence of chronic bacterial infection of upper respiratory tract in patient is determined by performing cultures of separated nose and oropharynx on nutrient mediums to detect monocultures and associations of bacteria of genus Staphylococcus, genus Streptococcus and Haemophilus in units of CFU/ml. Patient is diagnosed with the presence or absence of chronic persistent viral herpes infection by the content of specific IgG and IgG antibodies in U/ml in blood for detection of one or association of herpes viruses. Patient is diagnosed with the nature of chronic bacterial and viral infections accompanying somatic diseases of the digestive apparatus with determining the severity of intestinal dysbiosis and excessive bacterial growth of the colonic contents of the patient by sowing feces on nutrient media to detect presence of pathogenic flora in the form of haemolytic E.coli, lactose-negative E.coli and Staphylococcus aureus in CFU/g units. Presence of a secondary immunodeficient state of the patient is detected by the level of IgG, IgM, IgG in IgG and classes IgE in U/ml in blood serum for the severity of the primary chronic multifocal recurrent osteomyelitis. Patient's calcium-calcium metabolism disorders are detected by the level of total calcium, ionised ion and
