The present invention relates to the combination of pullulan or a derivative thereof with a polysaccharide chosen from hyaluronic acid, a salt or derivative thereof, alginic acid, a salt or derivative thereof and a mixture of these polysaccharides. It also relates to a mixture of cosmetic or pharmaceutical ingredients, a cosmetic or pharmaceutical composition and a detergent or hygiene product comprising this combination. It further relates to the use of this combination for reducing the insensible water losses and/or for increasing the water content of the skin and/or mucous membranes and/or for increasing and/or prolonging the content of cosmetic and/or pharmaceutical active ingredients in the skin and/or the mucous membranes and/or maintaining it over time, the use of this cosmetic composition for maintaining or improving the state of hydration of the skin, and/or for preventing or slowing down the appearance of the signs of cutaneous and/or mucosal dryness, and/or for treating cutaneous dryness conditions, and/or for preventing or reducing the appearance of wrinkles linked to cutaneous dryness, and/or for improving the comfort of dry skin and/or mucous membranes, and/or for treating skin and/or mucous membranes having an appearance that is rough to look at and/or to the touch, and also the use of the pharmaceutical composition in the treatment and/or the prevention of fissures and/or scurf or pityriasis alba and/or cracks and/or atopic dermatitis and/or ichthyosis and/or conditions of dryness of the skin or mucous membrane that accompany cutaneous pathologies.