The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections.本發明提供與單純皰疹病毒(HSV)之糖蛋白D特異性結合之抗體及多肽,及該等抗體及多肽用於治療或診斷HSV感染之用途。