The present invention relates to an active surface element (2) for improved treatment of damaged cell layers, wherein at least one topographically structured surface is moved along the pattern length (l) with a pattern period (p). It was provided on a substrate having a pattern with alternately extending ridges (5) and grooves (6), the pattern period (p) was smaller than 10 μm, and the pattern length (l) was larger than 1 mm. [Selection] Figure 1本発明は、損傷細胞層の改良された治療のための活性表面要素（２）に関し、少なくとも１つの地形的に構造化された表面を、パターン周期（ｐ）でパターン長（ｌ）に沿って延びる隆起（５）及び溝（６）を交互に備えたパターンを有する基板上に備え、前記パターン周期（ｐ）を１０μｍより小さく、前記パターン長（ｌ）を１ｍｍより大きくした。【選択図】 図１
