An air purification system formed from an adsorptive photo-catalytic oxidation device and a method of regenerating the oxidation device is disclosed. The air purification may be configured to be installed within an air duct of a central air handling system. The air purification system may also include an ultraviolet light emitted by the ultraviolet light source to breakdown captured volatile organic compounds into elemental carbon dioxide and water vapor and to irradiate air moving past the ultraviolet light and surfaces to reduce contaminants The ultraviolet light source may be positioned to expose the adsorptive photo-catalytic oxidation device to ultraviolet light emitted by the ultraviolet light source to breakdown captured volatile organic compounds into elemental carbon dioxide and water vapor and to irradiate air moving past the ultraviolet light to reduce contaminants.