HYUN, CHANG GU,현창구,YANG, EUN JIN,양은진,KANG, JI YONG,강지용,LEE, NAM HO,이남호
申请号：
KR1020100062441
公开号：
KR1020120001848A
申请日:
2010.06.30
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: An anti-inflammatory composition using 3-O-p-coumaroyl-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-O-beta-D-glucopyranosylpropanol is provided to suppress NO generation and PEG2 generation. CONSTITUTION: An anti-inflammatory composition contains 3-O-p-coumaroyl-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-O-beta-D-glucopyranosylpropanol as an active ingredient. The composition is a pharmaceutical composition or food composition. A pharmaceutical composition of iNOS inhibitor contains 3-O-p-coumaroyl-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-O-beta-D-glucopyranosylpropanol as an active ingredient. A pharmaceutical composition of COS-2 inhibitor contains 3-O-p-coumaroyl-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-O-beta-D-glucopyranosylpropanol as an active ingredient.본 발명은 NO 생성 억제 활성, PGE2 생성 억제 활성, 염증성 사이토카인 IL-6의 생성 억제 활성, iNOX 생성 억제 활성 및/또는 COX-2 생성 억제 활성을 가지는 3-O-p-쿠마로일-1-(4-하이드록시-3,5-디메톡시페닐)-1-O-β-D-글루코피라노실프로판올을 이용한 항염증성 조성물을 개시한다.
