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Methods of diagnosing diseases caused by or associated with neurofibrillary tangles by phosphospecific antibodies recognising Tau
专利权人:
AC IMMUNE S.A.;KATHOLIEKE UNIVERSITEIT LEUVEN
发明人:
Andrea Pfeifer,Andreas Muhs,Maria Pihlgren,Oskar Adolfsson,Fred Van Leuven
申请号:
US15337964
公开号:
US10066010B2
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
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