TSENG YUN-LONG,GUO LUKE S. S.,HONG KEELUNG,CHANG PO-CHUN,SHIH SHEUE-FANG
申请号:
NZ62345010
公开号:
NZ623450A
申请日:
2010.01.29
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
The disclosure relates to the method of using an ophthalmic drug delivery system in the manufacture of a medicament for treating an ophthalmic disease, wherein the ophthalmic drug delivery system comprises (a) a delivery vehicle comprising a phospholipid or a mixture of phospholipids, and cholesterol, wherein cholesterol is present in an amount of 10-33 mole percent relative to the delivery vehicle and (b) a water soluble therapeutic agent wherein 50-90% of the water soluble therapeutic agent is in non-associated form, and the weight ratio of the phospholipid and cholesterol in combination to the water soluble therapeutic agent is 5-80 to 1.