MCCOOEY BETH,MYERS DEANNA E.,LIU HUI F.,PETTY KRISTA MARIE,KELLEY BRIAN DAVID
申请号：
NZ60364811
公开号：
NZ603648A
申请日:
2011.05.25
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a method for purifying an antibody or immunoadhesin from a composition comprising the antibody or immunoadhesin and at least one contaminant, wherein the method comprises either (i) or (ii): (i) sequential steps of (a) loading the composition onto a cation exchange material at a loading density of greater than about 150 g/L of cation exchange material； and (b) loading a composition recovered from the cation exchange material onto a mixed mode material； or (ii) sequential steps of (a) loading the composition onto a mixed mode material； and (b) loading a composition recovered from mixed mode material onto a cation exchange material at a loading density of greater than about 150 g/L of cation exchange material.
