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用於治療CNS疾病的催產素受體激動劑
专利权人:
F.HOFFMANN LA ROCHE AG
发明人:
BISSANTZ, CATERINA,GRUNDSCHOBER, CHRISTOPHE,NETTEKOVEN, MATTHIAS,PLANCHER, JEAN-MARE -,VIFIAN, WALTER,卡泰麗娜‧比桑茨,克里斯托夫‧格倫德紹博,馬蒂亞斯‧內特科文,讓-馬克‧普朗謝,沃爾特‧維凡
申请号:
HK15109701.4
公开号:
HK1209032A
申请日:
2015.10.02
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The invention relates to the use of a compound of formula I wherein A1 is phenyl or a five or six membered hereroaryl group, containing 1, 2 or 3 heteroatoms, selected from N or S; R1 is hydrogen, lower alkyl, halogen, lower alkyl substituted by halogen or cycloalkyl; A2 is phenyl; R2 is halogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen, cyano, S-lower alkyl substituted by halogen, S(O)2-lower alkyl substituted by halogen; n is 1 or 2; or a pharmaceutically acceptable acid addition salt, or a racemic mixture or its corresponding enantiomer and/or optical isomers thereof, for the treatment of autism, stress, including post traumatic stress disorder, anxiety, including anxiety disorders and depression, schizophrenia, psychiatric disorders and memory loss, alcohol withdrawal, drug addiction and for the treatment of Prader-Willi Syndrome.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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