An inbred corn line designated IT7EE42 is disclosed. The invention relates to the plants and seeds of inbred corn line IT7EE42 and methods for producing a corn plant produced by crossing the inbred corn line IT7EE42 with itself or with another corn plant. The invention also relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants and plant parts produced by those methods. The invention also relates to corn cultivars and plant parts derived from inbred corn line IT7EE42 and to methods for producing other corn cultivars, lines, or plant parts derived from inbred corn line IT7EE42, and to the corn plants and parts derived from use of those methods. The invention further relates to hybrid corn seeds, plants, and plant parts produced by crossing inbred corn line IT7EE42 with another corn cultivar.