University of Rochester;Temple University -- of The Commonwealth System of Higher Education
发明人:
Dunman, Paul M.,Childers, Wayne
申请号：
AU2015339039
公开号：
AU2015339039B2
申请日:
2015.10.30
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in treating infections. Also provided herein are methods of using the compositions to inhibit a bacterial tRNA synthetase in a cell and to decolonize bacteria on a surface.
