An image processing unit includes a grayscale image creating unit, a shininess region removal unit, a region of interest tracing unit, and a time intensity curve measuring unit. The time intensity curve measuring unit includes a pixel value measuring unit which measures the pixel value of a specific point in the fluorescence image photographed by the fluorescence image pickup element, and a measurement position movement unit which moves the measurement position of the pixel value in the pixel value measuring unit in accordance with the region of interest traced by the region of interest tracing unit.
