The present invention relates to the use of an active compound that inhibits the mitochondrial breathing chain at the level of the b/c1 complex, in particular selected from strobilurin fungicides, for combating a complex of phytopathogenic fungi associated with the esca disease of grapevines.La présente invention concerne lutilisation dun composé actif inhibant la chaîne respiratoire mitochondriale au niveau du complexe b/c1 pour lutter contre les champignons phytopathogènes.