The present invention relates to a clip applier for clipping and dividing blood vessels, including: a handle a first jaw unit and a second jaw unit. The clip applier of the present invention can bring up two ligating clips at the same time with the first jaw unit and the second jaw unit, whereas the two clamping positions of the blood vessel can be clamped with the ligating clips simultaneously by the clip applier of the present invention in a single step, and thus the operating steps can be simplified, and the time involved with the surgical operation can be shortened.