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氯苯那敏(Chlorpheniramine)或其鹽的穩定化方法
专利权人:
发明人:
NEMOTO, FUKIKO,根本夫规子,根本夫規子
申请号:
TW103118783
公开号:
TWI608837B
申请日:
2014.05.29
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
The purpose of the present invention is to provide a technique with which adsorption, onto a container, of chlorpheniramine and/or a salt thereof in a solution having a pH of at least 7.0 and including chlorpheniramine and/or the salt thereof, is inhibited, and the chlorpheniramine and/or the salt thereof is stably maintained. By employing a polybutylene terephthalate-containing resin as a resin for configuring inner wall surfaces (such as a wall surface around an internal space of a pour-out part and/or a lid wall surface facing a pour-out opening of the pour-out part) of a container for accommodating a solution which includes chlorpheniramine and/or a salt thereof, and which has a pH of at least 7.0, adsorption of the chlorpheniramine and/or the salt thereof onto the inner wall surfaces can be inhibited, and the content of the chlorpheniramine and/or the salt thereof in the solution can be stably maintained.本發明之目的在於提供一種技術,為對於含氯苯那敏及/或其藥學上之鹽、且pH為7.0以上之液劑,可抑制氯苯那敏及/或其鹽吸附至容器並穩定維持的技術。關於含氯苯那敏及/或其鹽且pH為7.0以上之液劑,作為用以收容之容器,藉由採用含聚對苯二甲酸丁二酯之樹脂作為構成其內壁面(在注出部之內部空間壁面及/或蓋部中與注出部之注出口對向的壁面等)之樹脂,可抑制氯苯那敏及/或其鹽吸附至該內壁面,並可穩定維持液劑中之氯苯那敏及/或其鹽的含量。1‧‧‧容器本體2‧‧‧注出部3‧‧‧蓋部
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中国工程科技知识中心
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