MENICHINCHERI, MARIA M,ANGIOLINI, MAURO M,BERTRAND, JAY AARON JA,CARUSO, MICHELE M,POLUCCI, PAOLO P,QUARTIERI, FRANCESCA F,SALOM, BARBARA B,SALSA, MATTEO M,ZUCCOTTO, FABIO F,‧梅尼奇恩徹裡,‧安吉奧利尼,‧伯特蘭,‧卡魯索,‧波盧奇,‧夸爾蒂耶裡,‧薩隆,‧薩爾
申请号:
HK16101747.6
公开号:
HK1213883A
申请日:
2016.02.18
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention relates to substituted pyrimidinyl- and pyridinylpyrrolopyridinone compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions containing these compounds.