The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology
发明人:
Jianjun Cheng,Omid C. Farokhzad,Robert S. Langer,Benjamin A. Teply,Stephen E. Zale
申请号:
US13950804
公开号:
US08802153B2
申请日:
2013.07.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides targeted particles comprising a particle, one or more targeting moieties, and one or more therapeutic agents to be delivered and pharmaceutical compositions comprising inventive targeted particles. The present invention provides methods of designing, manufacturing, and using inventive targeted particles and pharmaceutical compositions thereof.