Paul E. HARRINGTON,Kate ASHTON,Sean P. BROWN,Matthew R. KALLER,Todd J. KOHN,Brian Alan LANMAN,Kexue LI,Yunxiao LI,Jonathan D. LOW,Ana Elena MINATTI,Alexander J. PICKRELL,Markian M. STEC,Joshua TAYGERL
申请号:
US16547747
公开号:
US20190381064A1
申请日:
2019.08.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I,or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.