Compounds derived from 2.3 - dihidromidazo (1,2-c) with Aminoalcohol substituted quinazoline compound and its use； intermediary； Pharmaceutical composition, Pharmaceutical Combination； and its use to treat hiperproliferativos Disorders and diseases associated with angiogenesis.
SCOTT, WILLIAM JOHNSTON,LIU, NINGSHU,MÖWES, MANFRED,HÄGEBARTH, ANDREA,MÖNNING, URSULA,BÖMER, ULF
申请号：
CL2013001295
公开号：
CL2013001295A1
申请日:
2013.05.10
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.COMPUESTOS DERIVADOS DE 2,3-DIHIDROIMIDAZO (1,2-C) QUINAZOLINA SUSTITUIDOS CON AMINOALCOHOLES； METODO PARA PREPARAR DICHOS COMPUESTOS； COMPUESTO INTERMEDIARIO； COMPOSICION Y COMBINACION FARMACEUTICA； Y SU USO COMO INHIBIDORES DE FOSFOTIDILINOSITOL-3-QUINASA (PI3K) PARA TRATAR TRASTORNOS HIPERPROLIFERATIVOS Y ENFERMEDADES ASOCIADAS A LA ANGIOGENESIS.
