Bill N. C. Sun;Yuliang Huang;Xiaoqiang Yan;Hongzhou Yang;Zhihua Huang
发明人:
Xiaoqiang Yan,Zhihua Huang,Hongzhou Yang,Bill N. C. Sun,Yuliang Huang
申请号：
US13114035
公开号：
US08557546B2
申请日:
2011.05.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be restored. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased.
