The invention comprises a system and method that may help place or position a component, such as an acetabular cup or a femoral component, during surgery. An example system may iteratively register a plurality of two-dimensional projections from a three-dimensional model of a portion of a patient, the three-dimensional model being generated from a data set of imaging information obtained at a neutral position. An example system may further score each two-dimensional projection against an intra-operative image by calculating a spatial difference between corresponding points. A two-dimensional projection having a minimum score reflecting the smallest distance between the corresponding points may be identified. Using the two-dimensional projection having the minimum score, an adjustment score reflecting a difference in the values representing the orientation of the three-dimensional model at the intra-operative projection position and values representing the orientation of the three-dimensional model at the neutral position may be calculated. The invention also comprises a system and method also comprising surgical method and workflow to improve the efficiency of a surgical procedure by intraoperatively acquiring a digital radiographic image, processing the digital radiographic image, and using information based on the radiographic image to make adjustments during the surgical procedure. A checklist of parameters may be displayed so that the surgeon can confirm all considerations have been made for the surgical procedure.