Methods and systems are disclosed for detecting a region of disturbed blood flow within a blood-filled lumen and indicating the region of disturbed blood flow using a disturbed blood flow indicator. The region of disturbed blood flow can be detecting by processing a plurality of data vectors acquired by an imaging device. The plurality of data vectors can also be processed to generate an intravascular image. The intravascular image can be displayed to include the disturbed blood flow indicator at a region on the displayed image corresponding to a detected region of disturbed blood flow.
