Stanley Chamberlain;John Vernachio;Karolina Madela;Christopher McGuigan;Jeff Hutchins;Mohamed Aljarah;Arnaud Gilles
发明人:
Stanley Chamberlain,Jeff Hutchins,Karolina Madela,Christopher McGuigan,John Vernachio,Mohamed Aljarah,Arnaud Gilles
申请号：
US13143098
公开号：
US08759318B2
申请日:
2010.01.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Phosphoramidate compounds derived from guanine bases having enhanced therapeutic potency are provided, and these compounds in particular have enhanced potency with respect to treatment of viral infections, such as hepatitis C virus. Pharmaceutical compositions, methods of preparing the compounds, and methods of using the compounds and compositions to treat viral infections are also provided.
