A monitoring disposable litter-less domestic-pet pad system and method for managing excreta of domestic pets, such as cats and dogs, performing tests for materials present in the excreta, indicating presence of such materials, and providing for secure and sanitary disposal, comprising an impermeable liner with an affixed absorbent pad having one or more incorporated indicator areas, where the indicator areas provide a level of indication ranging from a general overall level of concern in an alerting embodiment to a more detailed indication suitable for analysis by a veterinary practitioner in a diagnostic embodiment. The monitoring disposable litter-less domestic-pet pad system and method does not contaminate, denature, or otherwise compromise the urine or stool excreta, and therefore provides a secure and pleasant means of containing, saving, and transporting any such samples which are thought to warrant further analysis.
