The present invention discloses a method for performing CT imaging on a region of interest of an object under examination, comprising: acquiring the CT projection data of the region of interest acquiring the CT projection data of region B selecting a group of PI line segments covering the region of interest, and calculating the reconstruction image value for each PI line segment in the group and combining the reconstruction image values in all the PI line segments to obtain the image of the region of interest. The present invention further discloses a CT imaging device using this method and a data processor therein. Since the 2D/3D slice image of the region of interest can be exactly reconstructed and obtained as long as the X-ray beam covers the region of interest and the region B, it is possible to use a small-sized detector to perform CT imaging on the region of interest at any position of a large-sized object, which reduces to a great extent the radiation dose of the X-ray during the CT scanning.