David Thomso;Zhibin Li;John Lord;Hossein Razavi;Soojin Kim;Daniel Kuzmich;Jonathan Timothy Reeves;Christian Harcken;Thomas Wai-ho Lee;Pingrong Liu;Rajashekhar Betageri;Todd Bosanac;Michael Jason Burke
发明人:
Christian Harcken,Rajashekhar Betageri,Todd Bosanac,Michael Jason Burke,Soojin Kim,Daniel Kuzmich,Thomas Wai-ho Lee,Zhibin Li,Pingrong Liu,John Lord,Hossein Razavi,Jonathan Timothy Reeves,David Thomso
申请号:
US12477586
公开号:
US08268859B2
申请日:
2009.06.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of Formula (I)wherein R1, R2, X, and Y are as defined herein, or a tautomer, optical isomer, prodrug, co-crystal, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.