Systems and methods for identifying historical vasculature cases are disclosed. A method may use a case database and a processor. One such method comprises the step of retrieving an image of the vasculature, demographic factors, morphological factors, and hemodynamic factors of the individual. The image is segmented and a geometry is calculated using the processor. Fluid flow may be simulated based on the hemodynamic factors and the calculated geometry. Calculations and factors are stored in the case database and relevant cases are identified based on the calculated geometry of the vasculature, the simulated fluid flow, and the demographic factors in comparison to the cases in the case database.