SAVAGE MARY J,KINNEY GENE G,LIANG XIAOPING,CITRON MICHAEL,ROSEN LAURA B
申请号：
IN41/DELNP/2011
公开号：
IN2011DN00041A
申请日:
2011.01.03
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The invention provides a method for the treatment of a patient having a more severe form of Alzheimers disease (AD), where the severe form of AD is characterized by pathogenic deposits of amyloid beta peptide (Aß), comprising the administration of an immunogenic fragment of Aß capable of inducing an immune response in the form of antibodies to specific to the pathogenic deposits of Aß and, in particular, to neurotoxic forms of Aß including N-terminally truncated forms of Aß. The invention further provides a method for selecting a suitable immunogenic fragment of Aß for the treatment of a more severe form of AD.
