Alfred A. Avey,Appavu Chandrasekaren,Harold D. Doshan,Julio Perez,Yakov Rotshteyn
申请号：
US14018259
公开号：
US08853232B2
申请日:
2013.09.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides a compound of formula I:wherein R1, R2, R2′ and X− are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.
