#$%^&*AU2015224443B220170629.pdf#####The present invention provides for a method for treating a chronic brain injury or spasticity, comprising administering to a human who suffered a brain injury for at least 24 months previous, an initial dose containing a therapeutically effective amount of an antagonist of TNF. Similar methods relating to the treatment of chronic brain injury by administering an antagonist of interleukin or an antagonist of lymphotoxin are also provided.