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PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
专利权人:
JANSSEN PHARMACEUTICA N.V.
发明人:
APODACA, RICHARD,BREITENBUCHER, J
申请号:
NZ59014805
公开号:
NZ590148A
申请日:
2005.12.29
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are piperazinyl and piperidinyl urea compounds of formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described within the specification. An examples of a compound of formula (I) is 4-(3,4-dibromo-benzyl)-piperazine-1-carboxylic acid pyridine-4-ylamide. Further disclosed is a pharmaceutical composition comprising an effective amount of a compound of formula (I) and a pharmaceutically acceptable excipient, and the use of a compound of formula (I) in the preparation of a medicament for treating a disease, disorder, or medical condition mediated by FAAH activity.
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