STICKEL, JULIANE,KOWALEWSKI, DANIEL,RAMMENSEE, HANS-GEORG,STEVANOVIC, STEFAN
申请号:
CA2950827
公开号:
CA2950827A1
申请日:
2015.06.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to several novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.