A liquid ejection device includes an ejection tube, a gripping tube, a liquid chamber, a connection channel, and a pulsed-flow generating section. The ejection tube is a tube for ejecting liquid. The gripping section is an instrument attached to the ejection tube and gripped by a user. The liquid chamber is provided on the outside of the gripping section. The connection channel connects the liquid chamber and the ejection tube. The pulsed-flow generating section is provided on the outside of the gripping section and generates a pulsed flow in the liquid in the liquid chamber.