Jung Hwan LEE,Jong In KIM,Jong Hun IM,Jong Ook LEE,Jin Woo KIM
申请号:
US16608645
公开号:
US20200157543A1
申请日:
2018.04.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A composition for imaging a tumorous disease region includes a fluorescence- or radioactive isotope-labeled ERBB2 aptamer, wherein the ERBB2 aptamer labeled with a radioactive isotope or a fluorescent dye is used to image the tumorous disease region in vivo. The composition may include a labeled hybridized aptamer comprising an aptamer represented as formula 1 hybridized with a labeled-ODN represented as formula 2.