The invention relates to the use of thiosulphate in order to potentiate the anti pathogen effect of Lactobacillus bacteria said thiosulphate being in a quantity of at least 100 mg for 10 7 to 10 10 UFC of Lactobacillus. The invention also relates to a pharmaceutical composition comprising at least 100 mg of thiosulphate per gram combined with a strain of Lactobacillus crispatus as well as to the use thereof in the treatment of urogenital infections such as vaginosis thrush and urinary infections.