VASSILEVSKI, Alexander Alexandrovich,OPARIN, Peter Borisovich,KOROLKOVA, Yuliya Vladimirovna,MOSHAROVA, Irina Vladimirovna,SAVCHENKO, Ganna Anatolievna,BOYCHUK, Yaroslav Anatolievich,KRISHTAL, Oleg Al
申请号：
EP17877931
公开号：
EP3584254A4
申请日:
2017.05.31
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention refers to medicine and pharmacology, namely, to biologically active peptides, which modulate purinergic signaling. For that, the peptide with the following amino acid sequence is proposed:or a sequence with at least 90% homology hereto.Peptides in the invention can be used for prevention and treatment of diseases mediated by purinergic receptors. The peptides can be used for development of new drugs on their basis, for example, analgesics, as well for investigation of mechanisms of pain occurrence, for identification and testing of new modulators of P2X3 receptors. The peptides in the invention can be produced using chemical synthesis or biotechnologically using the nucleotide sequence of the corresponding gene.
